Everton make their first trip back to the Capital since the opening day of the season to take on West Ham at the London Stadium this weekend.
It's a fixture that pits the Blues against their ex-manager, David Moyes, once more, almost two years on from the Scot's only victory over his former club, shortly before he was unceremoniously dumped as the Hammers' boss and Sam Allardyce, his opposite number that day, was also jettisoned by Everton.
Moyes is, of course, back in charge at West Ham and looking for a second win after replacing Manuel Pellegrini and thrashing struggling Bournemouth in his first game at the helm. That was followed by injustice at Bramall Lane last time out where Robert Snodgrass's dramatic injury-time equaliser was wiped out by VAR and it's a smarting Hammers team that Toffees will be going up against.
Everton, meanwhile, returned to winning ways following the debacle at Anfield in the FA Cup with a narrow triumph over Brighton and, led by their own new gaffer, Carlo Ancelotti, they will travel south hoping to repeat their performance in this ground last season.
That 2-0 win over West Ham was, perhaps, their best away performance of Marco Silva's 18-month reign and it came amid an impressive run of form at the back end of last term that portended much better things than eventually unfolded under the Portuguese between August and December.
The victory over the East Londoners by the same scoreline at Goodison Park earlier this season was also one of the most complete performances under Silva and it hinted that he might finally have stumbled onto a winning attacking formula but things started to unravel again soon afterwards.
Nevertheless, it was a display that could provide a blueprint of sorts for Ancelotti to study as he prepares for this one, particularly given how impressive the Blues' two Brazilians were on the day. Bernard would suffer a knee injury at Brighton in the next game but he scored the opening goal against the Hammers and his showing against the Seagulls in the reverse fixture last weekend demonstrated that he is getting back into his stride.
Both he and Richarlison have the potential to be key figures for Everton but it is the ongoing lack of options in midfield that will continue to vex Ancelotti until one of Jean-Philippe Gbamin and André Gomes is fit enough to play. Both are back in training at Finch Farm undergoing individualised regimens to gradually bring them up to full fitness but, in the meantime, while Alex Iwobi is also sidelined and Mason Holgate is needed in defence, the Italian has to perm two from Tom Davies, Gylfi Sigurdsson and Fabian Delph.
Davies and Sigurdsson started against Brighton and Delph came on as a second-half substitute and the same approach could be employed by Ancelotti this weekend as well, particularly given Delph's on and off injury issues.
In defence, Yerry Mina is a doubt with what appears to be a minor injury and that will preclude the manager from rotating Holgate out of the side like he had planned to last week. Ancelotti is hopeful, nevertheless, that the Colombian will make it.
Moyes will make late checks on Arthur Masuaku (knee) and Felipe Anderson (rib) but Michail Antonio and Ryan Fredericks are both ruled out with hamstring problems. Darren Randolph, the goalkeeper West Ham just re-signed from Middlesbrough, is expected to go straight into the team to replace Lukas Fabianski who suffered a recurrence of a hip injury.
This will be an interesting test for Everton under Ancelotti but one that offers an opportunity against a team that has exhibited something of a soft centre this season and who were easily brushed aside in the first meeting between the two sides in October.
A repeat of the performance and result at Newcastle at the end of last year would be a welcome one given that the Barcodes are next up on Tuesday meaning that the Blues could take two big steps towards the top six in the next few days if they can pull off a couple of victories.
Update Richarlison and Sigurdsson have been ruled out with injury.
Kick-off: 3pm, Saturday, 18 January, 2020
Referee: Andre Marriner
VAR: Simon Hooper
Last Time: West Ham United. 0 - 2 Everton
Predicted Line-up: Pickford, Sidibé, Holgate, Keane, Digne, Davies, Sigurdsson, Bernard, Walcott, Richarlison, Calvert-Lewin